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GLP-1 hormonu, vcudun itah, tokluk, mide boalma hz ve kan ekeri dengesini dzenleyen nemli metabolik hormonlardan biridir
Small molecules can have different storage and handling requirements than peptides
doi: 10.1016/j.immuni.2025.04.002 113 Cembellin-PrietoALuoZKulagaHBaumgarthN
This leads to an imbalance in the glutathione/reactive oxygen species (ROS) axis and enhanced pyrimidine biosynthesis, which in turn sustains the cancer stem cell-like properties of lung cancer cells and drives the malignant progression of NSCLC ( Metabolites involved in the serine/glycine pathway are markedly depleted in the plasma of NSCLC patients after radiotherapy and in corresponding cellular models, indicating that tumor cells utilize these metabolites to facilitate DNA damage repair and cell survival
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