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Perspective on the Rx Pipeline: Diabetes and GLP-1 Agonists Situation Summary Initial therapy for individuals with T2DM who are at high risk for CVD, heart failure (HF) and/or chronic kidney disease is metformin and a glucagon-like peptide 1 (GLP-1) or sodium glucose transporter ligand 2 (SGLT-2)

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A 2025 study of 141 people with BED found that 70.2 percent of people treated with a combination of therapy and Vyvanse went into remission, making it almost twice as effective as medication or therapy alone

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