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Nutrients 14:279

These results suggest that semaglutide down-regulates several lipid-metabolism-related proteins in adipose tissues, it might be reducing PPAR pathway activity when PPAR gamma ( Based on the results of the study, we found 10 proteins significantly concentrated in lipid metabolism down-regulated in Sema/HFD group, including fatty acid transport and oxidation (CD36 FABP5, ACSL, ACOX3)

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