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The "Long R3" refers to two key modifications: an arginine substitution at position 3 and a 13-amino acid N-terminal extension
GSH is at 110 mM concentrations in all mammalian tissues (highest concentration in liver) as the most abundant non-protein thiol that protects against excessive oxidative stress
PMID: 16014563
Ortiz GG, Huerta M, Gonzalez-Usigli HA, Torres-Sanchez ED, Delgado-Lara DL, Pacheco-Moises FP, et al
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