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Gentamicin-induced nephrotoxicity triggers inflammation by activating the NF- transcription factor, which subsequently induces the production of pro-inflammatory cytokines IL-6 and TNF- 74,75 which in turn can exaggerate oxidative stress by producing more reactive oxygen species 32

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Sally Ward (Cancer Sciences Unit, Centre for Cancer Immunology, University of Southampton, Southampton, United Kingdom), and further incubated for 72 h at 2324 C and 160 RPM