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Over the following decades, glutathione became one of the most extensively investigated endogenous compounds within experimental research involving cellular metabolism, oxidative biochemistry and molecular signalling
The dimer interface is formed by the interaction between loop 2 of one monomer and loop 1 of the other, stabilized by hydrogen bonds and salt bridges, resulting in a more open and flexible active site pocket compared to other GCTs
A 2005 study by Finkley et al
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