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GLP-1R agonists are known to have beneficial effects in this large and steadily growing patient population, primarily through their effects on weight loss and insulin secretion, although emerging evidence suggests direct hepatic effects as well [152, 153]
Lysine at position 34 is replaced with arginine to permit selective acylation at Lys26
doi: 10.1016/S0140-6736(19)31271-1 31 MosenzonOBlicherTMRosenlundSErikssonJWHellerSHelsOHet al
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