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Note the lack of cell death propagation over time in female tubules
Both products can affect the digestive system, potentially causing overlapping gastrointestinal symptoms such as nausea, bloating, or altered bowel habits
Indirect comparisons using network meta-analysis suggest tirzepatide 15 mg produces approximately 5, 6 percentage points greater weight loss than semaglutide 2.4 mg, but trial populations differ in ways that complicate direct comparison
It also has a proven heart benefit: in a large trial, it reduced heart attacks and strokes by 20%
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