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Studies of Chinese Han population indicated that the T allele shown associated with schizophrenia as a risk allele 52 while a casecontrol association between the MTHFR C677T polymorphism and schizophrenia in a Japanese subjects research also demonstrated a strong linkage between the MTHFR C677T polymorphism and schizophrenia 53
Patients should be provided with clear safety advice , including when to temporarily discontinue SGLT2 inhibitors (during acute illness, dehydration, or 3 days before surgery), recognition of DKA symptoms (nausea, vomiting, abdominal pain, unusual fatigue), and management of genitourinary infections
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