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Similar trends were observed in a mouse model of pancreatic ductal adenocarcinoma (PDAC) ( LSL-Kras G12D/+ Trp53 f/f Pdx1 cre (KP / C) mice 28 ) and in humans with renal cell carcinoma 29 (Extended Data Fig
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Conversely, other anti-amyloid mAbs (e.g., aducanumab) have demonstrated more favourable outcomes in recent trials, culminating in an FDA endorsement for treatment of early AD stages (dementia or mild cognitive impairment) ( 3.2.1 Parkinson's disease (PD) PD is a CNS movement disorder that primarily occurs in people over 60 years, with an estimated 1% prevalence in the population belonging to this age group
Kosho, T., Nakamura, T., Kaneko, T
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