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Subcutaneous administration achieves brain concentrations twice plasma levels (t 1/2 ~10.5 hr) with no toxicity observed at 15 the therapeutic dose in rats
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The rapid induction of glutathione S-transferases AtGSTF2 and AtGSTF6 by avirulent Pseudomonas syringae is the result of combined salicylic acid and ethylene signaling
In contrast, SLC25A40 lacks the GSH-sensing cysteines of SLC25A39 and, as independently shown by Birsoys and Shens groups 11,12 , does not undergo post-translational regulation via the GSH-sensing stability loop that controls SLC25A39 protein levels
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