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NRTI-associated mitochondrial toxicity is a major adverse effect characterized by severe complications such as myopathy, peripheral neuropathy, hepatic failure, and lactic acidosis 178
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Post-race analysis revealed that MSM supplementation attenuated muscle and joint pain at clinically significant levels compared to the placebo, demonstrating its ability to protect against exertion-induced oxidative stress
"People who are living with these medications are swapping notes with each other in real time, sharing experiences that rarely make it into a doctor's office visit or an official report." As social media platforms have expanded, researchers say these discussions have become an increasingly valuable source of health-related information, even though collecting and analyzing the data has become more difficult over time
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