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However, taking periodic breaks (2-4 weeks off after each cycle) may help maintain effectiveness and prevent potential tolerance

Stampfer, S

In order of the number of reports (Table 4), the most common adverse events for liraglutide were nausea, hyperglycemia, vomiting, diarrhea, pancreatitis, decreased appetite, weight loss, headache, upper abdominal pain, and constipation

Context-dependent functional differences among AREs fit with findings from another group that combined high-throughput promoter-dependent drug screens and transcriptomics analyses to uncover that low doses of the chemotherapeutic doxorubicin downregulate cell cycle genes while high doses upregulate DNA damage response genes