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These pathological processes are intertwined, forming a vicious cycle of energy depletion-oxidative stress-inflammatory response-cell death-microcirculatory dysfunction, which not only causes AKI but also accelerates the progression of chronic pathologies such as renal interstitial fibrosis, significantly impacting prognosis and clinical outcomes [47, 48]
Bakirci, S., Dabague, J., Eder, L., McGonagle, D
Phelip JM et al
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