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showed improved results in patients with metastatic CRC and led to longer survival time compared with the control group [136]

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DSIP Research Delta sleep-inducing peptide (DSIP) is a neuropeptide consisting of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) that was first isolated from the cerebral venous blood of rabbits during sleep in the 1970s