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Clinically, in patients with renal failure, acute kidney injury, dialysis and other pathological states of renal function deterioration, renal reabsorption function is impaired, resulting in a significantly lower serum free carnitine concentration than that in healthy people [255], and the metabolic profile of acylcarnitine also changes significantly [256]
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The present analysis assessed the short-term cost-effectiveness of oral semaglutide versus empagliflozin 25 mg, sitagliptin 100 mg and liraglutide 1.8 mg for treatment of patients with type 2 diabetes, in terms of the cost per patient achieving treatment targets in the US setting
doi:10.1210/jc.2005-1536
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