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These have specific development challenges because they have very low particulate limits, they must not draw fluid back up the needle, they must not increase intraocular pressure, they have small dose volumes and precise dose accuracy, and they must be targeted very accurately
Se recomienda mantener la metformina y priorizar frmacos que disminuyan el peso (iSGLT-2 o aGLP-1)
[9] Liu Q, et al
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