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When used for weight management, semaglutide works by targeting the areas of the brain responsible for hunger regulation, helping people feel fuller for longer periods

Consideration of potential drug interactions and whether discussions have occurred with a primary care provider

2018;90(15):e1283e1290

Strengths of the current study include the large sample size, the detailed clinical assessment of depression and related characteristics, and the availability of the same data collected from participants still involved after 6 years of follow-up (totaling over 4,000 observations), which allowed further testing of the consistency of the detected associations