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19 DPP4 inhibitors have gained recognition as oral anti-diabetic medications for the treatment of type 2 diabetes

The exclusion criteria were: females who were pregnant or experiencing a menstrual period, type 2 diabetes treated using an insulin regimen, malignancy, hematopathy, active tuberculosis, peptic ulcer with gastric bleeding, binge-eating disorder, psychiatric disease, congestive heart failure, clinically relevant renal or hepatic insufficiency, unstable coronary artery disease, cancer or a history of cancer

Enhances production of GLP-1 (glucagon-like peptide-1), a hormone that regulates appetite, blood sugar levels, and insulin sensitivity