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Accordingly, it is essential to distinguish between normal, age-expected circadian adaptation and pathological circadian disruption
doi: 10.1016/j.trac.2020.115876 180
Hyperpigmentation was observed when this compound got oxidized and inactivated by factors such as heat, radiation and inflammation with consequent loss of the inhibitory effect on tyrosinase
Research highlights the crucial role of oxidative stress in the pathophysiology of PD [50, 66]
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