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[1] [2] For patients with documented hypersensitivity to other GLP-1 receptor agonists (such as semaglutide, dulaglutide, or liraglutide), cross-reactivity is uncertain due to differences in molecular structure

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21 Key patents such as US 10,278,923 (expiring 2034) and US 11,833,248 (expiring 2039) ensure that even after the core semaglutide compound patent expires in 2031, the oral market remains protected for nearly another decade

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