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Unlike earlier weight-management medicines, retatrutide is a triple receptor agonist , meaning it simultaneously targets three distinct hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors
In SURPASS-CVOT, MOUNJARO achieved the primary objective by demonstrating a non-inferior rate of major adverse cardiovascular events (MACE-3), including cardiovascular death, heart attack or stroke vs
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