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Clinical relevance of elastin in the structure and function of skin
Although information is still scanty, some genes and their protein products have been discovered to be of fundamental importance in controlling the cell function during oxidative stress conditions by acting at the genomic level and not simply as ROS scavengers
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The same reaction can occur on protein cysteine, and the formed GSNO group functions as important intermediate in NO metabolism, a critical player in fulfilling the biolgogical function of NO in signal transduction ( S -glutathionylation (Zeng et al., 2001) or thanks to catalytic activity of GGT generate S-nitrosocysteinylglycine that in turn can be cleaved by a membrane dipeptidase thus forming S -nitrosocysteine (S-NO)
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