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LEAN Trial: Liraglutide and NASH resolution The pioneering LEAN (Liraglutide Safety and Efficacy in patients with Non-alcoholic steatohepatitis) trial marked the first rigorous evaluation of GLP-1 agonists for NASH treatment
They fasted before arriving for the study, then they were given a snack bar to standardize caloric intake and stomach contents
At week 12, the absolute change in HbA1c from baseline was significantly greater in the tirzepatide treatment groups compared to the placebo group (placebo: +0.2% [0.21]
The Mexican National Nutrition Survey in 1999 showed a serum -tocopherol deficiency of nearly 30% in non-pregnant and pregnant women
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