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A recent head-to-head trial SURMOUNT-5, published in N Engl J Med, found that tirzepatide produced larger mean weight loss than semaglutide at the primary time point (tirzepatide 20.2% vs semaglutide 13.7%)

At TrimBody M.D., we know that being overweight might not cause discomfort but you put your health at risk in the long run

Common side effects include: Nausea Vomiting Diarrhea Constipation Abdominal discomfort More serious concerns under investigation include: Pancreatitis Gallbladder disease Severe gastroparesis Bowel obstruction Thyroid tumor concerns in susceptible populations Long-term safety beyond several years remains incompletely understood because these therapies are relatively new compared with decades of surgical outcome data