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In primate and human observational studies, the AEDG peptide and epithalamin have been investigated for their effects on pineal gland function in aged subjects

Zhu, H., Blake, S., Chan, K

Importantly, these metabolic improvements occurred without adverse cardiovascular effects, as the selective agonist did not increase blood pressure or heart rateside effects observed with less selective melanocortin compounds

However, as reassuring as all of this is, there are a couple of things to remain mindful of: Copper toxicity Because GHK-Cu contains copper, it does pose a potential risk of copper toxicity,12 the symptoms of which include abdominal pain, vomiting, chest pain, chills, cough, fever, general weakness, anemia, burning sensations, tremors, and a metallic taste in the mouth.13 The risk is small, as the concentrations of copper in the peptide are typically well within safe parameters, but its good to be aware of it