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25 Patients diagnosed with vitamin B 12 deficiency whose history and physical examination do not suggest an obvious dietary or malabsorptive etiology should be tested for pernicious anemia with anti-intrinsic factor antibodies (positive predictive value = 95%), particularly if other autoimmune disorders are present
If you have low levels of vitamin B12, you may experience sensations such as numbness or tingling in the hands, legs, or feet, difficulty walking caused by problems with balance, or having an inflamed, swollen tongue
Vitamin B supplementation can be needed in some cases, but injectable therapy should be based on confirmed deficiency or clinical need
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