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Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

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(2022) Investigation of the effects of berberine on bortezomib-induced sciatic nerve and spinal cord damage in rats through pathways involved in oxidative stress and neuro-inflammation

For PDX models, BM cells collected from each PDX recipient mouse were stained with anti-human CD33-PerCP/Cyanine5.5 (eBioscience) or anti-mouse CD45-Brilliant Violet 605 (Biolegend) and anti-human CD45-PE (eBioscience) antibodies at 4 C for 30 min