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In DR, GLP-1RAs vascular stabilization effects (via RhoA/ROCK inhibition) (Wei et al., 2022) could complement anti-VEGF therapy, yet their interaction in modulating angiogenesis remains unexplored
You're taking a detour when you need a direct highway
So: anyone circulating the 0.82 as proof of cardioprotection is reading a hazard ratio as though it were a p-value
Additionally, regulatory monitoring has identified safety concerns, including nearly 400 reported pancreatitis cases, with over 100 cases recorded in 2025 alone
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