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In animal cells the fate of ITCs is well characterized: conjugation to glutathione by GSTs resulting in its intracellular depletion and subsequent degradation of dithiocarbamates through enzymatic events catalysed by -glutamyltranspeptidase, cysteinylglycinase and N -acetyltransferase via the mercapturic acid pathway 76
Nutritional guru Alan Gaby, MD, has commented that the only way too much B12 will kill you is if you fill your bathtub with it and drown
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