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Silymarin, a Promising Pharmacological Agent for Treatment of Diseases, Iranian Journal of Basic Medical Sciences, US National Library of Medicine, National Institutes of Health

This biocompatibility minimizes toxicity concerns and was a key factor in their early adoption for nutraceutical applications

These trimers acquire DNA-binding activity and accumulate in the nucleus, where they bind to heat shock elements (HSEs) in the promoter regions of target genes and initiate HSP transcription (Feng et al., 2021)

ADVANCE recruited 1053 antiretroviral-naive nonpregnant adults without TB and randomized them equally to TAF/FTC+DTG, TDF/FTC+DTG, or TDF/FTC/efavirenz (EFV)