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A canonical mechanism involves the emergence of secondary mutations within drug targets
doi:10.3390/molecules27010324
doi: 10.3389/fpsyt.2021.669089 35 CazzolaM.RoglianiP.SalviS
GLP1 or E monotherapies in an obese model of PCOS Since the 10 nmol/kg dose of GLP1/E was at least as effective as higher doses in improving the metabolic profile of PCOS mice, we compared its beneficial effects in terms of body weight, fat mass, glucose tolerance, insulin sensitivity, and other traits vs
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