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They digest carbohydrates and trigger the release of GLP-1
mean dose, 1.02 g/day) compared to those who were not (124)
May aid brain function To date, results are mixed, with one 2018 study reporting 1500mg of l-carnitine (as acetyl-l-carnitine) taken daily for 28 weeks improved brain function in those with dementia
These include: Pre-existing constipation or slow transit constipation Inadequate dietary fibre intake Insufficient fluid consumption Reduced physical activity levels Concurrent medications with constipating effects (such as opioids, certain antidepressants, or iron supplements) Older age , where baseline colonic motility may already be reduced The severity of constipation often correlates with the dose of medication and may be more pronounced during dose escalation phases
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