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En los nios en fase de inmunotolerancia (HBeAg+ y ALT normal) sin otra patologa aadida, no se recomienda tratar, porque la probabilidad de respuesta es muy baja y requeriran muchos aos de tratamiento (dcadas) (14)
Januvia requires dose adjustment when eGFR falls below 45 mL/min/1.73m, with a reduced dose of 50mg daily for moderate impairment (eGFR 30-45) and 25mg daily for severe impairment (eGFR below 30)
Then, the mixture was incubated for 5 h at 4 C
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