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The FDA Adverse Event Reporting System (FAERS) contains reports of various gastrointestinal complications, though these reports have significant limitationsincluding underreporting, lack of denominator data, and inability to establish causality
Patients with pre-existing gastrointestinal conditions may experience different tolerability and should discuss their medical history with their healthcare provider
Significant weight loss from any cause can reduce bone mineral density, and muscle mass is directly correlated with bone health
Prioritize consistent sleep (79 hours nightly) and effective stress management to support adherence and metabolic health
