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Semaglutide, the active ingredient in Ozempic and Wegovy, works by slowing stomach emptying and activating brain satiety centerseffects that typically require consistent use to build and maintain

Pharmacologically, retatrutide is a triple incretin receptor agonist under investigation for its potential to activate three hormone receptors simultaneously: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor