Thus, we found that agonists that preserve higher levels of surface and total receptor, either by reduced internalization, increased recycling, or both, allow responsiveness retention during continuous or interrupted stimulation
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Without being limited thereto, such materials include diluents, binders and adhesives, lubricants, plasticizers, disintegrants, colorants, bulking substances, flavorings, sweeteners and miscellaneous materials such as buffers and adsorbents in order to prepare a particular medicated composition

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