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A recent randomized, placebo-controlled, double-blinded study in adolescents revealed that Orlistat did not significantly affect weight loss at six months
Firstly, subcutaneous semaglutide has already been proven to be superior to placebo in reducing cardiovascular risk, while the data on oral semaglutides cardiovascular benefits wont be available until 2024
That's also where diabetic peripheral neuropathy adds another layer of complexity impaired circulation and nerve signaling make the already-limited healing environment in foot tissue even harder to overcome without targeted support
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