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According to the MHRA-approved SmPC, semaglutide works by binding to GLP-1 receptors in multiple tissues, including the pancreas, where it enhances glucose-dependent insulin secretion, and in the brain, where it reduces appetite and food intake through effects on satiety centres

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Differences in dietary choices in patients who developed postprandial hyperinsulinemic hypoglycemia (dumping syndrome) after Roux-en-Y gastric bypass compared to healthy controls