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This unique clinical-molecular feature suggests that dysregulation of the TP53 signaling pathway is not only a key pathogenic mechanism of AML, but also a potential marker for molecular stratification and a target for targeted therapies, supporting the optimization of precision treatment strategies (12)
Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility
Clin Microbiol Rev (2009) 22(2):20223
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