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It is manufactured by Eli Lilly and intended for use alongside a reduced-calorie diet and increased physical activity to help lower body weight and reduce the risk of further weight gain

In trials, participants on 2.4 mg weekly lost on average about 15% of body weight over 68 weeks [2]

Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing