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1056 Scientific best practices in electronic clinical outcome assessments: a literature review from past to present Lindsay Hughes 1 , Jowita Marszewska 2 1 IQVIA, New York, New York, USA, 2 IQVIA, Cleveland, Ohio, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :1056 Aims Clinical Outcome Assessments (COAs) measure how patients feel, function, and survive, and can support label claims by demonstrating impact of treatment on patients Quality of Life (QOL)