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Studies indicate that magnesium may hold off cortical spreading depression, a catalyst for aura forms of migraines, while blocking neural pain signals and blood vessel narrowing

Compared to younger individuals, elderly patients typically exhibit reduced gut microbiota diversity, with a decline in beneficial bacterial groups such as Firmicutes and Actinobacteria and an increase in pathogenic groups such as Proteobacteria (Rondanelli et al., 2015

This physiological mechanism, which is useful for the post-translational modification of multiple proteins and for the regulation of signal and metabolic pathways, can turn harmful in case of oxidative stress, with the above-mentioned mitochondrial damage

The conjugation adduct obtained is then eliminated by the mercapturic acid pathway (Fig