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8.5 Geriatric Use In the pool of glycemic control trials, 1,229 (30%) patients treated with semaglutide tablets were 65 years of age and over and 199 (5%) patients treated with semaglutide tablets were 75 years of age and over [see Clinical Studies (14)]
A meta-analysis of these GLP-1 RA cardiovascular outcome trials found that GLP-1 RAs reduced major adverse cardiovascular events (MACE) by 12%, heart failure hospitalizations by 9%, and all-cause death by 12% 9
These effects occur through natural biochemical pathways, offering a blend of cosmetic and wellness benefits
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