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According to NICE guidance (NG145), treatment with levothyroxine is typically recommended when TSH is 10 mIU/L on two separate occasions, with individualised decisions for lower TSH levels based on symptoms and risk factors
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After taking account of more than 50 factors, including weight, lifestyle habits, family history and laboratory results, premature menopause remained linked to a 12.3 per cent higher risk of hypertension than menopause after age 45
This matters for cardiovascular risk assessment and is one reason some researchers switch between medications based on their specific metabolic goals and side effect tolerance
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