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NFE2L2 plays a pivotal role in regulating antioxidant genes involved in both GPX4-dependent (e.g., GPX4 and SLC7A11) and GPX4 independent pathways (e.g., AIFM2 and MT1G [metallothionein 1G]) [34, 83, 156]
The association of genetically predicted l-carnitine with CAD in men not in women is possibly due to a smaller number of CAD cases in women therefore a lower power (as shown in Additional file 1: Table S6)
H.ChenX
Vu KD, Lavis VR, Strom S, Faderl SH, Konopleva M, Thomas DA, Gruschkus S, Andreeff M , Kantarjian H
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