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This triggers several beneficial effects: Enhanced insulin secretion from the pancreas when blood glucose levels are elevated Reduced glucagon release , which prevents the liver from producing excess glucose Slowed gastric emptying , meaning food moves more slowly from the stomach into the intestines Increased satiety signals to the brain, reducing appetite and food intake These combined mechanisms help lower blood glucose levels in people with type 2 diabetes and promote weight loss in those with obesity
Although randomized controlled trials have demonstrated the efficacy of incretin-based therapies, real-world comparative data in adults with overweight or obesity without diabetes remain limited
In a study of people with obesity following a reduced-calorie diet, researchers found that those who ate more fiber lost more weight
In addition, studies have explored its association with molecular signals linked to tissue remodeling, suggesting a supportive role in recovery mechanisms (16)
