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Diabetologia (2005) This randomized, double-blind, placebo-controlled crossover study evaluated the effects of pramlintide on satiety and food intake in two populations: 11 insulin-treated men with type 2 diabetes (mean BMI 28.9) and 15 obese non-diabetic men (mean BMI 34.4)

Internal standards are designed to support analytical consistency, not pharmaceutical, metabolic, or therapeutic use

Nature 390 , 4551 (1997)

NICE recommends GLP-1 medications for type 2 diabetes when other treatments have not achieved adequate control, or for weight management in adults with a BMI of 30 kg/m or above (with weight-related comorbidities) as part of a specialist multidisciplinary service