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The inclusion in our network analysis of the AMPLITUDE-O and EMPEROR-P data have modified the conclusions of the most recent similar analysis [15] indicating that SGLT-2 inhibitors increased the risk of stroke as compared with GLP-1RA and that GLP-1RA are superior to DPP-4 inhibitors as for nonfatal MI

Collectively, these extra-hepatic effects create a favorable systemic metabolic environment that indirectly but substantially benefits hepatic steatosis and MASH

Ultimately, the decision to start a GLP-1 should be made with a trusted healthcare professional who understands both the science and the unique challenges of menopause

For GHK-CU and AHK-CU, start with 1-2% concentration regardless of which type you choose