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9 There is a need for further longitudinal studies to confirm safety, which may slow adoption in broader patient populations

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This is again opposed to our observation of LSD1 preserving glutathione levels, however no LSD1 inhibitors were used in their investigation so it cannot be said if binding sites on LSD1 play a role or if the differential response is due to tissue type

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RNA-sequencing analysis revealed that the chemical treatment strongly suppressed the expression of programmed cell death- and autophagy-related genes

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A.et al (2017)

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